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Thalidomide-5-NH-PEG2-NH2 hydrochloride - CAS 2357110-58-6
Thalidomide-5-NH-PEG2-NH2 hydrochloride - CAS 2357110-58-6
SKU:MF-0120073-01
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Product Details
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Bioactivity
Thalidomide-5-NH-PEG2-NH2 hydrochloride is a cereblon ligand based on Thalidomide, designed to recruit CRBN proteins. It has the capability to be linked with target protein ligands via a linker, facilitating the formation of PROTAC molecules, such as THAL-SNS-032.
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Target
Apoptosis, Others, Autophagy, E3 Ligase Ligand-Linker Conjugate
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Related Pathways
Apoptosis, Others, Autophagy, PROTAC
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CAS Number
2357110-58-6
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Molecular Formula
C19H25ClN4O6
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Molecular Weight
440.88
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SMILES
O=C1N(C(=O)C=2C1=CC(NCCOCCOCCN)=CC2)C3C(=O)NC(=O)CC3.Cl
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC