Thalidomide-5-OH - CAS 64567-60-8

Thalidomide-5-OH (2- (2,6-dioxopiperidin-3-yl) -5-hydroxyisoindoline-1,3-dione) is the Thalidomide-based cereblon ligand that used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTAC.

Autophagy, Ligand for E3 Ligase, Apoptosis

PROTAC, Apoptosis, Autophagy

64499

0.9894

C13H10N2O5

274.23

O=C1N(C(=O)C=2C1=CC(O)=CC2)C3C(=O)NC(=O)CC3

-20°C

Ice Packs

PROTAC