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Thalidomide-5- (PEG2-amine) - CAS 2550398-08-6
Thalidomide-5- (PEG2-amine) - CAS 2550398-08-6
SKU:MF-0114820-01
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Product Details
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Bioactivity
Thalidomide-5- (PEG2-amine) is a Thalidomide analogue that includes an E3 ligase ligand substituted with a terminal amine group. The amine group can react with NHS esters or carboxylic acids in the presence of EDC or HATU. The PEG spacer enhances water solubility.
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Target
E3 Ligase Ligand-Linker Conjugate
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Related Pathways
PROTAC
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CAS Number
2550398-08-6
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Molecular Formula
C20H24N4O7
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Molecular Weight
432.427
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SMILES
O=C(NCCOCCOCCN)C1=CC=C2C(=O)N(C(=O)C2=C1)C3C(=O)NC(=O)CC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC