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Thalidomide-5-propargyne-NH2 hydrochloride - CAS 2490402-62-3

Thalidomide-5-propargyne-NH2 hydrochloride - CAS 2490402-62-3

MF-0039780-01

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Product Details

  • Bioactivity

    Thalidomide-5-propargyne-NH2 hydrochloride, a Thalidomide-derived cereblon ligand, is utilized in recruiting CRBN protein and can be linked to a protein ligand via a linker to form PROTACs [for protein degradation].

  • Target

    E3 Ligase Ligand-Linker Conjugate, Autophagy, Others, Apoptosis

  • Related Pathways

    PROTAC, Autophagy, Apoptosis, Others

  • CAS Number

    2490337

  • Molecular Formula

    C16H14ClN3O4

  • Molecular Weight

    347.753

  • SMILES

    Cl.NCC#Cc1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC