Thalidomide-azetidine-C-PIP-C-boc - CAS 2589699-87-4

Thalidomide-azetidine-C-PIP-C-boc is a conjugate of E3 ligase ligand and linker, comprising Thalidomide and the corresponding linker. As a Cereblon ligand, Thalidomide-azetidine-C-PIP-C-boc recruits CRBN protein and acts as a crucial intermediate in the synthesis of complete PROTAC molecules.

Ligand for E3 Ligase, Autophagy

Autophagy, PROTAC

2589699-87-4

C27H35N5O6

525.6

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=C(C2)N4CC(CN5CCN(CC(OC(C)(C)C)=O)CC5)C4

-20°C

Ice Packs

PROTAC