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Molfinity

Thalidomide-N-methylpiperazine - CAS 2924858-30-8

Thalidomide-N-methylpiperazine - CAS 2924858-30-8

MF-0110182-01

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Product Details

  • Bioactivity

    Thalidomide-N-methylpiperazine functions as an E3 Ligase Ligand-Linker Conjugate and is instrumental in the synthesis of PROTAC MLKL Degrader-2. This compound demonstrates antinecroptotic activity in human cell lines and effectively degrades MLKL in the HT-29 xenograft mouse model.

  • Target

    E3 Ligase Ligand-Linker Conjugate

  • Related Pathways

    PROTAC

  • CAS Number

    2924820

  • Molecular Formula

    C18H20N4O4

  • Molecular Weight

    356.38

  • SMILES

    O=C1NC(=O)C(N2C(=O)C3=CC=C(C=C3C2=O)N4CCN(C)CC4)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC