Thalidomide-NH-C4-NH2 TFA - CAS 2093387-50-7

Thalidomide-NH-C4-NH2 TFA (compound 29c) is a conjugate composed of an E3 ligase ligand-linker that integrates a Thalidomide-based cereblon ligand and a linker moiety. This compound is used as a component in PROTAC BRD2/BRD4 degrader-1, a highly potent and selective degrader targeting BET proteins BRD4 and BRD2[1].

Others, E3 Ligase Ligand-Linker Conjugate, Autophagy, Apoptosis

Apoptosis, Others, Autophagy, PROTAC

2093330

C19H21F3N4O6

458.39

O=C(O)C(F)(F)F.O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCCCN)C3C2=O)CC1

-20°C

Ice Packs

PROTAC