Thalidomide-NH-C6-NH-Boc - CAS 2093536-13-9

Thalidomide-NH-C6-NH-Boc is a synthesized E3 ligase ligand-linker conjugate containing a cereblon ligand derived from Thalidomide and a linker used in the synthesis of MI-389 [compound 22], a highly effective phthalimide PROTAC degrader developed from the multi-targeted receptor tyrosine kinase inhibitor sunitinib.

Apoptosis, Autophagy, E3 Ligase Ligand-Linker Conjugate, Others

Apoptosis, Others, Autophagy, PROTAC

2093514

C24H32N4O6

472.542

CC(C)(C)OC(=O)NCCCCCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

-20°C

Ice Packs

PROTAC