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Thalidomide-NH-C9-NH2 hydrochloride - CAS 2305936-77-8
Thalidomide-NH-C9-NH2 hydrochloride - CAS 2305936-77-8
SKU:MF-0156475-01
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Product Details
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Bioactivity
Thalidomide-NH-C9-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein. This compound can be conjugated to a protein-targeting ligand via a linker, enabling the formation of proteolysis-targeting chimeras (PROTACs) [1].
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Target
Others, Ligand for E3 Ligase
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Related Pathways
Others, PROTAC
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CAS Number
2305851
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Molecular Formula
C22H31ClN4O4
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Molecular Weight
450.96
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SMILES
Cl.O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCCCCCCCCN)C3C2=O)CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC