Thalidomide-NH- (CH2) 2-NH2 TFA - CAS 1957235-67-4

Thalidomide-NH- (CH2) 2-NH2 TFA, an alkyl-modified derivative of Thalidomide, functions as a Cereblon ligand to recruit CRBN proteins and serves as a crucial intermediate in the synthesis of CRBN-based PROTAC molecules targeting the SHP2 protein.

E3 Ligase Ligand-Linker Conjugate, Others, Autophagy, Apoptosis

Autophagy, PROTAC, Others, Apoptosis

1957164

C17H17F3N4O6

430.34

NCCNC1=C2C(=O)N(C3C(=O)NC(=O)CC3)C(=O)C2=CC=C1.OC(=O)C(F)(F)F

-20°C

Ice Packs

PROTAC