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Thalidomide-O-amido-C11-COOH - CAS 2473270-96-9
Thalidomide-O-amido-C11-COOH - CAS 2473270-96-9
SKU:MF-0115976-01
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Product Details
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Bioactivity
Thalidomide-O-amido-C11-COOH (Compound IMiD acid 1) is a compound that acts as an E3 ligase ligand and linker for the CRBN (Cereblon) conjugate. This compound is useful in synthesizing PROTACs targeting the degradation of DOT1L.
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Target
E3 Ligase Ligand-Linker Conjugate
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Related Pathways
PROTAC
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CAS Number
2473165
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Molecular Formula
C27H35N3O8
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Molecular Weight
529.58
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SMILES
O=C(O)CCCCCCCCCCCNC(=O)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC