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Thalidomide-O-amido-PEG1- (C1-PEG) 2-C2-NH2 - CAS 2435572-48-6
Thalidomide-O-amido-PEG1- (C1-PEG) 2-C2-NH2 - CAS 2435572-48-6
SKU:MF-0047339-01
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Product Details
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Bioactivity
Thalidomide-O-amido-PEG1- (C1-PEG) 2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.
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Target
Others, E3 Ligase Ligand-Linker Conjugate, Autophagy, Apoptosis
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Related Pathways
Apoptosis, Others, Autophagy, PROTAC
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CAS Number
2435518
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Molecular Formula
C25H34N4O9
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Molecular Weight
534.566
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SMILES
NCCOCCCOCCCOCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC