Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride - CAS 2245697-84-9

Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate, incorporates a cereblon ligand derived from Thalidomide and a 3-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes small molecules to induce protein degradation [1].

Apoptosis, Autophagy, E3 Ligase Ligand-Linker Conjugate, Others

Autophagy, PROTAC, Apoptosis, Others

2245604

C23H31ClN4O9

542.97

Cl.O=C(NCCOCCOCCOCCN)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3

-20°C

Ice Packs

PROTAC