Thalidomide-O-C8-COOH - CAS 2225148-51-4

Thalidomide-O-C8-COOH, also known as Cereblon ligand 3, is a Thalidomide-derived compound that serves as a Cereblon (CRBN) ligand for the targeted recruitment of CRBN protein. It can be coupled via a linker to another ligand to create proteolysis-targeting chimeras (PROTACs) [1].

Others, E3 Ligase Ligand-Linker Conjugate, Autophagy, Apoptosis

PROTAC, Others, Apoptosis, Autophagy

2225093

C22H26N2O7

430.45

O=C(O)CCCCCCCCOC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3

-20°C

Ice Packs

PROTAC