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Thalidomide-O-PEG1-OH - CAS 2416234-31-4

Thalidomide-O-PEG1-OH - CAS 2416234-31-4

MF-0114615-01

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Product Details

  • Bioactivity

    Thalidomide-O-PEG1-OH is a PROTAC linker characterized by its combination of Thalidomide with O-ethyl. Thalidomide acts as a ligand for the E3 ubiquitin ligase, leading to protein ubiquitination and subsequent proteasomal degradation. Additionally, the hydroxy group serves as a versatile handle, facilitating the formation of more complex structures through various reactions.

  • Target

    PROTAC Linker

  • Related Pathways

    PROTAC

  • CAS Number

    2416199

  • Molecular Formula

    C15H14N2O6

  • Molecular Weight

    318.281

  • SMILES

    O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCO)C3C2=O)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC