Thalidomide-O-PEG2-propargyl - CAS 2098487-52-4

Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical compound that has been synthesized as a conjugate of an E3 ligase ligand and a linker. It incorporates the cereblon ligand based on Thalidomide, along with a 2-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes ligand-induced protein degradation [1].

Others, Autophagy, E3 Ligase Ligand-Linker Conjugate, Apoptosis

PROTAC, Autophagy, Others, Apoptosis

2098431

C20H20N2O7

400.38

O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCOCCOCC#C)C3C2=O)CC1

-20°C

Ice Packs

PROTAC