Thalidomide-pinacolborane - CAS 2229725-98-6

Thalidomide-pinacolborane is a Thalidomide analogue featuring a boronic acid pinacol ester, also known as a Bpin group, commonly used in Suzuki reactions. The molecule acts as an activator of E3 ligase, facilitating the ubiquitination of proteins, thereby targeting them for proteolytic degradation.

Ligand for E3 Ligase

PROTAC

2229621

C19H21BN2O6

384.191

O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)B4OC(C)(C)C(O4)(C)C

-20°C

Ice Packs

PROTAC