Thalidomide-PIP- (R) C-pyrrolidine-boc - CAS 2839668-87-8

Thalidomide-PIP- (R) C-pyrrolidine-boc is a conjugate comprising an E3 ligase ligand and a linker, specifically containing Thalidomide and its corresponding linker. This compound functions as a Cereblon ligand, facilitating the recruitment of the CRBN protein, and is a crucial intermediate in synthesizing complete PROTAC molecules.

Autophagy, Ligand for E3 Ligase

PROTAC, Autophagy

2839668-87-8

C27H35N5O6

525.6

O=C1N(C(=O)C=2C1=CC(=CC2)N3CCN(C[C@@H]4CN(C(OC(C)(C)C)=O)CC4)CC3)C5C(=O)NC(=O)CC5

-20°C

Ice Packs

PROTAC