Thalidomide-propargyl - CAS 2098487-39-7

Thalidomide-propargyl, a Thalidomide-derived Cereblon ligand, facilitates the recruitment of Cereblon. It can be attached to the protein ligand via a linker, producing IMiD-containing PROTACs.

Apoptosis, Ligand for E3 Ligase, Autophagy, E3 Ligase Ligand-Linker Conjugate

Autophagy, PROTAC, Apoptosis

2098441

0.9514

C16H12N2O5

312.28

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC#C

-20°C

Ice Packs

PROTAC