Thalifendine chloride - CAS 4668-19-3

Thalifendine chloride is a metabolite of berberine, wherein the methoxy group at the C-10 position undergoes demethylation by CYP51. It exhibits cytotoxicity against P-388 mouse leukaemia cells (ED50 = 0.84 μM) and demonstrates weak inhibitory activity against Plasmodium falciparum.

Parasite, Drug Metabolite

Metabolism, Microbiology/Virology

4646

C19H16ClNO4

357.79

O(C)C1=C2C=[N+]3C(C=4C(=CC5=C(C4)OCO5)CC3)=CC2=CC=C1O.[Cl-]

-20°C

Ice Packs

Small Compound