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Theliatinib - CAS 1353644-70-8
Theliatinib - CAS 1353644-70-8
SKU:MF-0094591-01
Regular price
$45.88 USD
Regular price
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$45.88 USD
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Product Details
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Bioactivity
Theliatinib, a potent and highly selective EGFR inhibitor, with anti-tumor activity. Ki of 0.05 nM for wild type EGFR, and IC50s of 3 and 22 nM for EGFR and EGFR T790M/L858R mutant, respectively.
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Target
EGFR
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Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis
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CAS Number
1353566
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Purity
0.9967
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Molecular Formula
C25H26N6O2
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Molecular Weight
442.51
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SMILES
[H][C@]12CCN(C)[C@@]1([H])CN(C2)C(=O)Nc1cc2c(Nc3cccc(c3)C#C)ncnc2cc1OC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound