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Molfinity

Theliatinib - CAS 1353644-70-8

Theliatinib - CAS 1353644-70-8

SKU:MF-0094591-01

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  • Bioactivity

    Theliatinib, a potent and highly selective EGFR inhibitor, with anti-tumor activity. Ki of 0.05 nM for wild type EGFR, and IC50s of 3 and 22 nM for EGFR and EGFR T790M/L858R mutant, respectively.

  • Target

    EGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis

  • CAS Number

    1353566

  • Purity

    0.9967

  • Molecular Formula

    C25H26N6O2

  • Molecular Weight

    442.51

  • SMILES

    [H][C@]12CCN(C)[C@@]1([H])CN(C2)C(=O)Nc1cc2c(Nc3cccc(c3)C#C)ncnc2cc1OC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound