Thi-DPPY - CAS 2307699-34-7

Thi-DPPY is a potent, orally active JAK3 inhibitor that acts on BTK (IC50: 62.4 nM), JAK (IC50: 1.38 nM) . Thi-DPPY is anti-proliferative against HBE cells. Thi-DPPY has anti-inflammatory effects in vivo. Thi-DPPY has shown research potential in idiopathic pulmonary fibrosis (IPF) .

Others, JAK

Chromatin/Epigenetic, Angiogenesis, Stem Cells, Others, JAK/STAT signaling, Tyrosine Kinase/Adaptors

2307658

C28H28ClN5O4S

566.07

O(C1=C2C(=NC(NC3=CC(Cl)=C(OCCCN4CCOCC4)C=C3)=N1)C=CS2)C5=CC(NC(C=C)=O)=CC=C5

-20°C

Ice Packs

Small Compound