Thienodolin - CAS 149127-27-5

Thienodolin, an alkaloid discovered in S. albogriseolus, enhances root and shoot growth in rice seedlings at a concentration of 4 μM, but at 40 μM, it inhibits growth. It suppresses LPS-induced nitric oxide (NO) production with an IC50 of 17.2 μM, diminishes LPS-induced rises in inducible NO synthase (iNOS) levels, and hinders LPS-induced IκB degradation in RAW 264.7 macrophages.

Others, STAT, NF-κB

NF-κB, Others, JAK/STAT signaling, Stem Cells

149127-27-5

C11H7ClN2OS

250.7

O=C(N)C=1SC=2NC=3C=C(Cl)C=CC3C2C1

-20°C

Ice Packs

Natural Product