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Thio-ITP - CAS 27652-34-2
Thio-ITP - CAS 27652-34-2
SKU:MF-0152885
Regular price
$901.17 USD
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$901.17 USD
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Product Details
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Bioactivity
Thio-ITP, also known as 6-Thioinosine 5'-triphosphate, is a competitive inhibitor of RNA polymerase activity. It exhibits a strong apparent affinity towards the polymerases, with Ki values of 40.9 μM for RNA polymerase I and 38.0 μM for RNA polymerase II.
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Target
DNA/RNA Synthesis, Others
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Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others
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CAS Number
27616
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Molecular Formula
C10H15N4O13P3S
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Molecular Weight
524.23
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SMILES
O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cnc2c1[nH]cnc2=S
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound