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Molfinity

Thio-ITP - CAS 27652-34-2

Thio-ITP - CAS 27652-34-2

SKU:MF-0152885

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  • Bioactivity

    Thio-ITP, also known as 6-Thioinosine 5'-triphosphate, is a competitive inhibitor of RNA polymerase activity. It exhibits a strong apparent affinity towards the polymerases, with Ki values of 40.9 μM for RNA polymerase I and 38.0 μM for RNA polymerase II.

  • Target

    DNA/RNA Synthesis, Others

  • Related Pathways

    DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others

  • CAS Number

    27616

  • Molecular Formula

    C10H15N4O13P3S

  • Molecular Weight

    524.23

  • SMILES

    O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cnc2c1[nH]cnc2=S

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound