Thiophene-2 - CAS 420089-51-6

Thiophene-2 (TP2) is a targeted inhibitor of polyketide synthase 13 (Pks13), specifically designed to disrupt mycolic acid biosynthesis, effectively inducing rapid cell death in mycobacteria. It demonstrates notable anti-tuberculosis activity and exhibits a minimum inhibitory concentration (MIC) value of 1 μM against Mycobacterium tuberculosis.

Others, Antibacterial

Microbiology/Virology, Others

420089-51-6

C18H14F5NO3S

419.37

O=C(OC)C1=C(SC2=C1CCCCC2)NC(=O)C=3C(F)=C(F)C(F)=C(F)C3F

-20°C

Ice Packs

Small Compound