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Molfinity

THK-5105 - CAS 1374107-46-6

THK-5105 - CAS 1374107-46-6

SKU:MF-0049684-01

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  • Bioactivity

    THK-5105, an arylquinoline derivative, demonstrates high binding affinity for tau fibrils, protein aggregates, and tau-rich Alzheimer's disease (AD) brain homogenates, indicating its potential as a tau imaging PET (Positron Emission Tomography) probe with the radiolabeled version, 18F-THK-5105 [1].

  • Target

    Others, Microtubule Associated

  • Related Pathways

    Cytoskeletal Signaling, Others

  • CAS Number

    1374055

  • Molecular Formula

    C20H21FN2O2

  • Molecular Weight

    340.39

  • SMILES

    O(CC(CF)O)C1=CC2=C(N=C(C=C2)C3=CC=C(N(C)C)C=C3)C=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound