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Molfinity

THK-5117 - CAS 1374107-54-6

THK-5117 - CAS 1374107-54-6

SKU:MF-0041700-01

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  • Bioactivity

    THK-5117 is an arylquinoline derivative with the potential as a PET probe for tau imaging. THK-5117 shows high binding affinity to tau fibrils with a Ki value of 10.5 nM. THK-5117 also shows high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD) brain homogenates [1].

  • Target

    Microtubule Associated, Others

  • Related Pathways

    Others, Cytoskeletal Signaling

  • CAS Number

    1374047

  • Molecular Formula

    C19H19FN2O2

  • Molecular Weight

    326.36

  • SMILES

    O(CC(CF)O)C1=CC2=C(N=C(C=C2)C3=CC=C(NC)C=C3)C=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound