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Molfinity

THK01 - CAS 2226941-26-8

THK01 - CAS 2226941-26-8

MF-0154976-01

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Product Details

  • Bioactivity

    THK01, a potent ROCK2 inhibitor, exhibits IC50 values of 5.7 nM for ROCK2 and 923 nM for ROCK1, respectively. It effectively targets the ROCK2-STAT3 signaling pathway to inhibit breast cancer metastasis, making it valuable for breast cancer research [1].

  • Target

    ROCK, Others

  • Related Pathways

    Stem Cells, Cell Cycle/Checkpoint, Others, Cytoskeletal Signaling

  • CAS Number

    2226907

  • Molecular Formula

    C20H13N3O2

  • Molecular Weight

    327.34

  • SMILES

    O=C1C2=C3C(=C4C(=C2CN1)C=5C(N4)=CC=CC5)NC=6C3=CC(O)=CC6

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound