Molfinity

THRX-144644 - CAS 2442519-59-5

SKU:MF-0146482-01

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Product Details

Bioactivity
THRX-144644, a lung-restricted ALK5 inhibitor, exhibits a potent IC50 value of 0.14 nM and circumvents systemic toxicities linked to TGFβ pathway inhibition.
Target
Others, TGF-beta/Smad
Related Pathways
Others, Stem Cells
CAS Number
2442455
Molecular Formula
C26H28ClF2N7
Molecular Weight
512
SMILES
FC1=C(C=2C(=CNN2)C3=NC4=C(C=C3)N=CC(NCCN5CCN(C(C)C)CC5)=C4)C=C(Cl)C(F)=C1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound