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THS-044 - CAS 62054-67-5
THS-044 - CAS 62054-67-5
SKU:MF-0031791-01
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$64.57 USD
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$64.57 USD
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Product Details
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Bioactivity
THS-044 (N-[2-Nitro-4- (Trifluoromethyl) phenyl]morpholin-4-Amine) binding stabilizes the HIF2α PAS-B folded state with a kd of 2 μM and regulates HIF2 activity in endogenous and clinical settings.
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Target
HIF/HIF Prolyl-Hydroxylase, HIF
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Related Pathways
Metabolism, Angiogenesis, Chromatin/Epigenetic
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CAS Number
61982
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Purity
>99.99%
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Molecular Formula
C11H12F3N3O3
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Molecular Weight
291.23
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SMILES
[O-][N+](=O)c1cc(ccc1NN1CCOCC1)C(F)(F)F
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound