Thymidine-5'-O- (α, β-methylene) diphosphate sodium - CAS 71370-60-0

Thymidine-5'-O- (α, β-methylene) diphosphate (TMP-CP), a hydrolytically stable derivative of TDP, functions as an inhibitor of thymidine kinase (Ki = 23 μM) . It serves as a precursor in the synthesis of α, β-methylene-2'-deoxythymidine 5'-triphosphate, which is a non-cleavable substrate for DNA polymerase.

Others, DNA/RNA Synthesis

Cell Cycle/Checkpoint, Others, DNA Damage/DNA Repair

71370-60-0

C11H15N2O10P2.3Na

466.16

CC(C(NC1=O)=O)=CN1[C@H]2C[C@H](O)[C@@H](COP(CP([O-])([O-])=O)([O-])=O)O2.[Na+].[Na+].[Na+]

-20°C

Ice Packs

Small Compound