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THZ1 - CAS 1604810-83-4
THZ1 - CAS 1604810-83-4
SKU:MF-0038461-01
Regular price
$90.81 USD
Regular price
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$90.81 USD
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Product Details
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Bioactivity
THZ1 (CDK7 inhibitor) is a selective covalent inhibitor of CDK7, exhibiting binding affinity to the cysteine residue located at the outer end of the classical kinase domain, thus conferring high selectivity for CDK7, with an IC50 of 3.2 nM.
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Target
CDK
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Related Pathways
Cell Cycle/Checkpoint
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CAS Number
1604723
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Purity
0.9927
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Molecular Formula
C31H28ClN7O2
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Molecular Weight
566.05
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SMILES
CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound