THZ1-R - CAS 1621523-07-6

THZ1-R is a non-covalent active analogue of THZ1, with the acrylamide group removed from THZ1, losing its ability to covalently bind to the C312 cysteine residue of CDK7. Its CDK7 inhibitory activity is weaker than that of THZ1.

CDK

Cell Cycle/Checkpoint

1621523-07-6

C31H30ClN7O2

568.07

O=C(NC=1C=CC=C(C1)NC=2N=CC(Cl)=C(N2)C3=CNC=4C=CC=CC43)C5=CC=C(C=C5)NC(=O)CCCN(C)C

-20°C

Ice Packs

Small Compound