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TIE-2/VEGFR-2 kinase-IN-3 - CAS 433224-09-0

TIE-2/VEGFR-2 kinase-IN-3 - CAS 433224-09-0

SKU:MF-0157501-01

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  • Bioactivity

    TIE-2/VEGFR-2 kinase-IN-3, a benzimidazole derivative, is a potent inhibitor of tyrosine kinase receptors TIE-2 and VEGFR-2, with IC50 values of 6.9 nM and 3.5 nM, respectively. This compound is useful for angiogenesis research [1].

  • Target

    Others, Tie-2, VEGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, Others, Angiogenesis

  • CAS Number

    433224-09-0

  • Molecular Formula

    C23H17F4N5O3S

  • Molecular Weight

    519.47

  • SMILES

    N(C(OC)=O)C=1NC=2C(N1)=CC=C(SC3=CC=C(NC(NC4=CC(C(F)(F)F)=CC=C4F)=O)C=C3)C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound