TIE-2/VEGFR-2 kinase-IN-4 - CAS 433224-29-4

TIE-2/VEGFR-2 kinase-IN-4, a benzimidazole derivative, is a potent inhibitor of the tyrosine kinase receptors TIE-2 and VEGFR-2, with IC50 values of 5.2 nM and 5.1 nM, respectively. This compound is utilized in angiogenesis research [1].

VEGFR, Others, Tie-2

Others, Angiogenesis, Tyrosine Kinase/Adaptors

433191

C26H17F4N5O4

539.44

N(C(=O)C1=CC=CO1)C=2NC=3C(N2)=CC=C(OC4=CC=C(NC(NC5=CC(C(F)(F)F)=CC=C5F)=O)C=C4)C3

-20°C

Ice Packs

Small Compound