Molfinity
Tilifodiolide - CAS 126724-95-6
Tilifodiolide - CAS 126724-95-6
SKU:MF-0038336
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Product Details
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Bioactivity
Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreasing the intestinal fluid accumulation and vasorelaxant effects mediated by nitric oxide and cyclic guanosine monophosphate, it also showed anxiolytic and antidepressant effects by the partial involvement of gamma-Aminobutyric acid (GABA) receptors and the possible participation of α2-adrenoreceptors, respectively.
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Target
TNF, IL Receptor, GABA Receptor
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Related Pathways
Membrane transporter/Ion channel, Neuroscience, Apoptosis, Immunology/Inflammation
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CAS Number
126623
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Molecular Formula
C20H16O5
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Molecular Weight
336.34
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SMILES
O=C1OCC=C1[C@H]1CCc2ccc3C(=O)O[C@@H](c4ccoc4)c3c2C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product