Timcodar mesylate - CAS 183313-30-6

Timcodar mesylate (VX-853-2) and its analog VX-710 function as inhibitors of mammalian multidrug-resistant bacterial efflux pumps, specifically blocking the efflux of ethidium bromide in Staphylococcus aureus. This capability suggests that Timcodar mesylate may boost the efficacy of antibiotics by impeding the bacterial efflux pumps, therefore lowering the minimum inhibitory concentrations of certain antibiotics against Gram-positive pathogens including Staphylococcus aureus, Enterococcus, and Streptococcus pneumoniae.

Others, Antibacterial

Others, Microbiology/Virology

183313-30-6

C45H53ClN4O12S2

941.5

CS(=O)(O)=O.ClC(C=C1)=CC=C1C[C@H](N(C)C(C(C2=CC(OC)=C(C(OC)=C2)OC)=O)=O)C(N(CC3=CC=CC=C3)C(CCC4=CC=NC=C4)CCC5=CC=NC=C5)=O.CS(=O)(O)=O

-20°C

Ice Packs

Small Compound