Tinlorafenib - CAS 2573781-75-4

Tinlorafenib (PF-07284890) (compound 10) is an orally active, central nervous system (CNS) -permeable BRAF kinase inhibitor targeting BRAFV600E (IC50: 4.25 nM) and V600K (IC50: 2.7 nM) . Tinlorafenib is applicable for studying BRAF-associated malignant and benign tumors of the CNS and extracranial malignancies.

Raf, Others, ERK

Others, MAPK

2573702

C19H19ClF2N4O3S

456.89

CC1=C2C(=CC=C1NC3=C(Cl)C(NS(CCCF)(=O)=O)=CC=C3F)N=CN(C)C2=O

-20°C

Ice Packs

Small Compound