Tirabrutinib hydrochloride - CAS 1439901-97-9

Tirabrutinib hydrochloride is a potent, highly selective, and irreversible oral BTK inhibitor. Tirabrutinib hydrochloride irreversibly covalently binds to Bruton tyrosine kinase (BTK) in B cells and exhibits potent in vitro cytotoxicity against many types of B cell malignancies, as well as in vivo antitumor activity in mouse models [1].

Apoptosis, BTK

Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors

1439901-97-9

0.9995

C25H23ClN6O3

490.94

Cl.CC#CC(=O)N1CC[C@H](C1)n1c2ncnc(N)c2n(-c2ccc(Oc3ccccc3)cc2)c1=O

-20°C

Ice Packs

Small Compound