TL033 TFA - CAS 2746343-70-2

TL033 TFA is a component of an antibody-drug conjugate (drug-linker conjugate for ADC) . It comprises a linker and a bioactive small molecule toxin. TL033 TFA can be conjugated with the antibody Sacituzumab (anti-Trop-2) to synthesize BT001021, which exhibits anticancer activity against various cancers, including breast cancer, non-small cell lung cancer (NSCLC), and gastric cancer.

Drug-Linker Conjugates for ADC

Antibody-drug Conjugate/ADC Related

2746271

C78H104F3N13O25S2

1744.86

C(C(O)=O)(F)(F)F.O=C1N2C(C=3C(C2)=C(CCN(S(C)(=O)=O)C(C)C)C=4C(N3)=CC=CC4)=CC5=C1COC(=O)[C@]5(OC(OCC6=CC=C(NC([C@@H](NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN7C=C(CNC(CCCC#CC=8C=NC(S(C)(=O)=O)=NC8)=O)N=N7)=O)=O)CCCCN)=O)C=C6)=O)CC

-20°C

Ice Packs

Small Compound