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TLR4-IN-C34-C2-COOH - CAS 1159408-54-4

TLR4-IN-C34-C2-COOH - CAS 1159408-54-4

SKU:MF-0044384-01

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  • Bioactivity

    TLR4-IN-C34-C2-COO is a linker compound incorporating the TLR4 inhibitor TLR4-IN-C34, effectively inhibiting TLR4 activity in enterocytes and macrophages, and mitigating systemic inflammation in murine models of endotoxemia and necrotizing enterocolitis.

  • Target

    Others, TLR, PROTAC Linker

  • Related Pathways

    Others, Immunology/Inflammation, PROTAC

  • CAS Number

    1159350

  • Molecular Formula

    C19H29NO11

  • Molecular Weight

    447.43

  • SMILES

    O(C(C)=O)[C@H]1[C@@H](OC(C)=O)[C@@H](COC(C)=O)O[C@@H](OCCCCC(O)=O)[C@@H]1NC(C)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC