TLR4/NF-κB-IN-1 - CAS 3050836-94-4

TLR4/NF-κB-IN-1 (Compound 7x) is an orally bioavailable inhibitor targeting the TLR4/NF-κB signaling pathway, with anti-inflammatory properties and the ability to cross the blood-brain barrier. It can alleviate LPS-induced acute neuroinflammation in mice and downregulate the protein expression of TLR4, P-NF-κB, and P-IκB-α.

NF-κB, IκB/IKK, TLR

NF-κB, Immunology/Inflammation

3050738

C20H15FN6O

374.37

O=C1NC2=CC=C(C=C2N1)NC3=NC=NC4=C3C=CN4CC5=CC=C(F)C=C5

-20°C

Ice Packs

Small Compound