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TLR7/8 agonist 9 - CAS 2649170-17-0

TLR7/8 agonist 9 - CAS 2649170-17-0

SKU:MF-0147059-01

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  • Bioactivity

    TLR7/8 agonist 9 (Compound 25a), with EC50 values of 40 nM for hTLR7 and 23 nM for hTLR8, demonstrates anti-tumor properties and enhances the efficacy of PD-1/PD-L1 blockade treatments, making it valuable for cancer immunotherapy research [1].

  • Target

    TLR, Others

  • Related Pathways

    Immunology/Inflammation, Others

  • CAS Number

    2649153

  • Molecular Formula

    C20H26N6O

  • Molecular Weight

    366.46

  • SMILES

    N(CCOC)C=1C2=C(C=CC(CC3=CC=C(CN(C)C)C=C3)=N2)N=C(N)N1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound