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TLR7/8 agonist 9 - CAS 2649170-17-0
TLR7/8 agonist 9 - CAS 2649170-17-0
SKU:MF-0147059-01
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$1,778.67 USD
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$1,778.67 USD
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Product Details
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Bioactivity
TLR7/8 agonist 9 (Compound 25a), with EC50 values of 40 nM for hTLR7 and 23 nM for hTLR8, demonstrates anti-tumor properties and enhances the efficacy of PD-1/PD-L1 blockade treatments, making it valuable for cancer immunotherapy research [1].
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Target
TLR, Others
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Related Pathways
Immunology/Inflammation, Others
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CAS Number
2649153
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Molecular Formula
C20H26N6O
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Molecular Weight
366.46
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SMILES
N(CCOC)C=1C2=C(C=CC(CC3=CC=C(CN(C)C)C=C3)=N2)N=C(N)N1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound