TLR7 agonist 12 - CAS 2389988-47-8

TLR7 agonist 12 (example 20), a purine nucleoside analog, functions as a TLR7 agonist with broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include DNA synthesis inhibition, apoptosis induction, among others [1] [2].

Nucleoside Antimetabolite/Analog, Others

Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

2389933

C14H19N5O8

385.33

O=C1N(C2=C(N1CCCC(O)=O)C(=O)N=C(N)N2)[C@@H]3O[C@H](CO)[C@H](O)[C@H]3O

-20°C

Ice Packs

Small Compound