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TLR7 agonist 14 - CAS 2832199-45-6
TLR7 agonist 14 - CAS 2832199-45-6
SKU:MF-0147180-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
Compound 17b, a TLR7 agonist also known as TLR7 agonist 14, exhibits high potency with an EC50 of 18 nM. It effectively activates mouse macrophages and human peripheral blood mononuclear cells (hPBMCs) at low-nanomolar concentrations [1].
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Target
Others, TLR
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Related Pathways
Others, Immunology/Inflammation
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CAS Number
2832148
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Molecular Formula
C29H36N6O3
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Molecular Weight
516.63
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SMILES
C(N1C=2C=3C(N=C(N)C2N=C1CCCC)=CC=CC3)C4=CC=C(NC(CCNC(OC(C)(C)C)=O)=O)C=C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound