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TLR7 agonist 20 - CAS 3029695-00-6

TLR7 agonist 20 - CAS 3029695-00-6

SKU:MF-0148048-01

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  • Bioactivity

    TLR7 agonist20 (compound 23) is an imidazoquinoline analogue. It acts as a potent and specific TLR7 agonist with an EC50 value of 0.23 μM for hTLR7. This compound exhibits strong adjuvant activity on spike antibody levels and induces a robust T helper cell 1 (Th1) response, increasing IgG2b and IgG2c alongside IgG1.

  • Target

    TLR

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    3029695-00-6

  • Molecular Formula

    C22H24N4O

  • Molecular Weight

    360.45

  • SMILES

    OCC1=CC=C(C=C1)CN2C(=NC=3C(=NC=4C=CC=CC4C32)N)CCCC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound