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TLR7 agonist 20 - CAS 3029695-00-6
TLR7 agonist 20 - CAS 3029695-00-6
SKU:MF-0148048-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
TLR7 agonist20 (compound 23) is an imidazoquinoline analogue. It acts as a potent and specific TLR7 agonist with an EC50 value of 0.23 μM for hTLR7. This compound exhibits strong adjuvant activity on spike antibody levels and induces a robust T helper cell 1 (Th1) response, increasing IgG2b and IgG2c alongside IgG1.
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Target
TLR
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Related Pathways
Immunology/Inflammation
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CAS Number
3029695-00-6
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Molecular Formula
C22H24N4O
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Molecular Weight
360.45
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SMILES
OCC1=CC=C(C=C1)CN2C(=NC=3C(=NC=4C=CC=CC4C32)N)CCCC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound