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TLR8 antagonist-1 - CAS 1111460-83-3

TLR8 antagonist-1 - CAS 1111460-83-3

MF-0112692-01

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Product Details

  • Bioactivity

    TLR8 antagonist 1 (Compound 10) is a selective antagonist that can inhibit TLR8 mediated inflammation and signaling pathways. TLR8 antagonist 1 reduces MyD88 recruitment and inhibits NF - κ B and IRF pathways, exhibiting certain anti-inflammatory activity.

  • Target

    TLR, NF-κB, MyD88

  • Related Pathways

    Immunology/Inflammation, NF-κB

  • CAS Number

    1111374

  • Molecular Formula

    C21H29N3O4

  • Molecular Weight

    387.47

  • SMILES

    O=C(NC1CCN(CC)CC1)C2=CC=C(OCC=3C(=NOC3C)C)C(OC)=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound