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Molfinity

TM-1 - CAS 921099-13-0

TM-1 - CAS 921099-13-0

MF-0138276-01

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Product Details

  • Bioactivity

    TM-1 is a potent pyruvate dehydrogenase kinase (PDHK) inhibitor that inhibits the activity of PDHK1 (IC50: 2.97 μM) and PDHK2 (IC50: 5.2 μM) . TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation and inhibits cancer cell proliferation.

  • Target

    Others, Dehydrogenase

  • Related Pathways

    Metabolism, Others

  • CAS Number

    921086

  • Molecular Formula

    C26H32N2O6

  • Molecular Weight

    468.54

  • SMILES

    COc1ccc(cc1OC)-c1c(C)c2ccc(OCCN3CCN(CCO)CC3)cc2oc1=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound