TM5441 sodium - CAS 2319722-53-5

TM5441, an orally bioavailable plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 values ranging from 13.9 to 51.1 μM, effectively induces intrinsic apoptosis across multiple human cancer cell lines. Additionally, it mitigates Nω-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence [1] [2].

Others, Apoptosis, PAI-1

Apoptosis, Metabolism, Others

2319722-53-5

C21H16ClN2NaO6

450.8

N(C(COCC(NC1=C(C(O)=O)C=C(Cl)C=C1)=O)=O)C=2C=C(C=CC2)C=3C=COC3.[Na]

-20°C

Ice Packs

Small Compound