TMDJ-035 - CAS 2681302-83-8

TMDJ-035 is a selective inhibitor of the RyR2 (ryanodine receptor 2) . It effectively suppresses abnormal calcium (Ca^2+) waves and transients in isolated cardiomyocytes derived from mice with RyR2 mutations. As such, TMDJ-035 serves as a valuable tool in research for elucidating the gating mechanisms and dynamics of the RyR2 channel [1].

Calcium Channel

Membrane transporter/Ion channel, Metabolism

2681302-83-8

C16H12F3N5O

347.29

O=C(N(C1=CC=C(F)C=C1)C)CN2N=NC(=N2)C3=CC(F)=CC(F)=C3

-20°C

Ice Packs

Small Compound